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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Wikstrom JD, Twig G, Shirihai OS.  2009.  What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy? Int J Biochem Cell Biol. Abstract
Molina AJ, Wikstrom JD, Stiles L, Las G, Mohamed H, Elorza A, Walzer G, Twig G, Katz S, Corkey BE, Shirihai OS.  2009.  Mitochondrial Networking Protects Beta Cells from Nutrient Induced Apoptosis. Diabetes. Abstract
Wang T, Si Y, Shirihai OS, Schultz V, Corkey RF, Hu L, Deeney JT, Guo W, Corkey BE.  2009.  Respiration in Adipocytes is Inhibited by Reactive Oxygen Species. Obesity. Epub ahead Abstract
2008
Twig G, Hyde B, Shirihai OS.  2008.  Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta. 1777(9):1092-7. Abstract
Elorza A, Hyde B, Mikkola HK, Collins S, Shirihai OS.  2008.  UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis. J Biol Chem. 283(45):30461-70. Abstract
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, Shirihai OS.  2008.  Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. Embo J. 27(2):433-46. Abstract
Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ.  2008.  Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 14(2):144-53. Abstract
Danial NN, Walensky LD, Zhang CY, Choi CS, Fisher JK, Molina AJ, Datta SR, Pitter KL, Bird GH, Wikstrom JD, Deeney JT, Robertson K, Morash J, Kulkarni A, Neschen S, Kim S, Greenberg ME, Corkey BE, Shirihai OS, Shulman GI, Lowell BB, Korsmeyer SJ.  2008.  Dual role of proapoptotic BAD in insulin secretion and beta cell survival. Nat Med. 14(2):144-53. Abstract
2007
Wikstrom JD, Katzman SM, Mohamed H, Twig G, Graf SA, Heart E, Molina AJ, Corkey BE, de Vargas LM, Danial NN, Collins S, Shirihai OS.  2007.  beta-Cell mitochondria exhibit membrane potential heterogeneity that can be altered by stimulatory or toxic fuel levels. Diabetes. 56(10):2569-78. Abstract
Sheftel AD, Zhang AS, Brown C, Shirihai OS, Ponka P.  2007.  Direct interorganellar transfer of iron from endosome to mitochondrion. Blood. 110(1):125-32. Abstract
Haigh SE, Twig G, Molina AA, Wikstrom JD, Deutsch M, Shirihai OS.  2007.  PA-GFP: a window into the subcellular adventures of the individual mitochondrion. Novartis Found Symp. 287:21-36;discussion36-46. Abstract
2006
Twig G, Graf SA, Wikstrom JD, Mohamed H, Haigh SE, Elorza A, Deutsch M, Zurgil N, Reynolds N, Shirihai OS.  2006.  Tagging and tracking individual networks within a complex mitochondrial web with photoactivatable GFP. Am J Physiol Cell Physiol. 291(1):C176-84. Abstract
Heart E, Corkey RF, Wikstrom JD, Shirihai OS, Corkey BE.  2006.  Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells. Am J Physiol Endocrinol Metab. 290(1):E143-E148. Abstract
2005
Twig G, Graf SA, Messerli MA, Smith PJ, Yoo SH, Shirihai OS.  2005.  Synergistic amplification of beta-amyloid- and interferon-gamma-induced microglial neurotoxic response by the senile plaque component chromogranin A. Am J Physiol Cell Physiol. 288(1):C169-75. Abstract
2004
Katzman SM, Messerli MA, Barry DT, Grossman A, Harel T, Wikstrom JD, Corkey BE, Smith PJ, Shirihai OS.  2004.  Mitochondrial metabolism reveals a functional architecture in intact islets of Langerhans from normal and diabetic Psammomys obesus. Am J Physiol Endocrinol Metab. 287(6):E1090-9. Abstract