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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Peyot ML, Guay C, Latour MG, Lamontagne J, Lussier R, Pineda M, Ruderman NB, Haemmerle G, Zechner R, Joly E, Madiraju SR, Poitout V, Prentki M.  2009.  Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. J Biol Chem. 284(25):16848-59. Abstract
Harbilas D, Martineau LC, Harris CS, Adeyiwola-Spoor DC, Saleem A, Lambert J, Caves D, Johns T, Prentki M, Cuerrier A, Arnason JT, Bennett SA, Haddad PS.  2009.  Evaluation of the antidiabetic potential of selected medicinal plant extracts from the Canadian boreal forest used to treat symptoms of diabetes: part II. Can J Physiol Pharmacol. 87(6):479-92. Abstract
Delghingaro-Augusto V, Nolan CJ, Gupta D, Jetton TL, Latour MG, Peshavaria M, Madiraju SR, Joly E, Peyot ML, Prentki M, Leahy J.  2009.  Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass. Diabetologia. 52(6):1122-32. Abstract
Bendayan M, Londono I, Kemp B, Hardie GD, Ruderman N, Prentki M.  2009.  Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immuno-electron Microscopy. J Histochem Cytochem. Abstract
Coletta DK, Sriwijitkamol A, Wajcberg E, Tantiwong P, Li M, Prentki M, Madiraju M, Jenkinson CP, Cersosimo E, Musi N, DeFronzo RA.  2009.  Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. Diabetologia. Abstract
Lamontagne J, Pepin E, Peyot ML, Joly E, Ruderman NB, Poitout V, Madiraju SR, Nolan CJ, Prentki M.  2009.  Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations. Endocrinology. 150(8):3465-74. Abstract
Peyot ML, Gray JP, Lamontagne J, Smith PJ, Holz GG, Madiraju SR, Prentki M, Heart E.  2009.  Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PLoS One. 4(7):e6221. Abstract
2008
Prentki M, Madiraju SR.  2008.  Glycerolipid metabolism and signaling in health and disease. Endocr Rev. 29(6):647-76. Abstract
Nolan CJ, Prentki M.  2008.  The islet beta-cell: fuel responsive and vulnerable. Trends Endocrinol Metab. 19(8):285-91. Abstract
Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.  2008.  Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb J. 22(6):1905-13. Abstract
Dallaire P, Bellmann K, Laplante M, Gelinas S, Centeno-Baez C, Penfornis P, Peyot ML, Latour MG, Lamontagne J, Trujillo ME, Scherer PE, Prentki M, Deshaies Y, Marette A.  2008.  Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57(8):1999-2011. Abstract
2007
Przybytkowski E, Joly E, Nolan CJ, Hardy S, Francoeur AM, Langelier Y, Prentki M.  2007.  Upregulation of cellular triacylglycerol - free fatty acid cycling by oleate is associated with long-term serum-free survival of human breast cancer cells. Biochem Cell Biol. 85(3):301-10. Abstract
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, Boutin P, Vincent D, Belisle A, Hadjadj S, Balkau B, Heude B, Charpentier G, Hudson TJ, Montpetit A, Pshezhetsky AV, Prentki M, Posner BI, Balding DJ, Meyre D, Polychronakos C, Froguel P.  2007.  A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 445(7130):881-5. Abstract
Guay C, Madiraju SR, Aumais A, Joly E, Prentki M.  2007.  A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. J Biol Chem. 282(49):35657-65. Abstract
Lamontagne J, Masiello P, Marcil M, Delghingaro-Augusto V, Burelle Y, Prentki M, Nolan CJ.  2007.  Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats. Appl Physiol Nutr Metab. 32(2):241-8. Abstract
2006
Nolan CJ, Leahy JL, Delghingaro-Augusto V, Moibi J, Soni K, Peyot ML, Fortier M, Guay C, Lamontagne J, Barbeau A, Przybytkowski E, Joly E, Masiello P, Wang S, Mitchell GA, Prentki M.  2006.  Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia. 49(9):2120-30. Abstract
Martineau LC, Couture A, Spoor D, Benhaddou-Andaloussi A, Harris C, Meddah B, Leduc C, Burt A, Vuong T, Mai Le P, Prentki M, Bennett SA, Arnason JT, Haddad PS.  2006.  Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine. 13(9-10):612-23. Abstract
Kwan EP, Xie L, Sheu L, Nolan CJ, Prentki M, Betz A, Brose N, Gaisano HY.  2006.  Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55(5):1421-9. Abstract
Prentki M, Nolan CJ.  2006.  Islet beta cell failure in type 2 diabetes. J Clin Invest. 116(7):1802-12. Abstract
Nolan CJ, Madiraju MS, Delghingaro-Augusto V, Peyot ML, Prentki M.  2006.  Fatty acid signaling in the beta-cell and insulin secretion. Diabetes. 55 Suppl 2:S16-23. Abstract
Spoor DC, Martineau LC, Leduc C, Benhaddou-Andaloussi A, Meddah B, Harris C, Burt A, Fraser MH, Coonishish J, Joly E, Cuerrier A, Bennett SA, Johns T, Prentki M, Arnason JT, Haddad PS.  2006.  Selected plant species from the Cree pharmacopoeia of northern Quebec possess anti-diabetic potential. Can J Physiol Pharmacol. 84(8-9):847-58. Abstract
Cheyssac C, Dina C, Lepretre F, Vasseur-Delannoy V, Dechaume A, Lobbens S, Balkau B, Ruiz J, Charpentier G, Pattou F, Joly E, Prentki M, Hansen T, Pedersen O, Vaxillaire M, Froguel P.  2006.  EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families. Diabetes. 55(4):1171-6. Abstract
2005
Assifi MM, Suchankova G, Constant S, Prentki M, Saha AK, Ruderman NB.  2005.  AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. Am J Physiol Endocrinol Metab. 289(5):E794-800. Abstract
Pelletier A, Joly E, Prentki M, Coderre L.  2005.  Adenosine 5'-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes. Endocrinology. 146(5):2285-94. Abstract
Neve B, Fernandez-Zapico ME, Ashkenazi-Katalan V, Dina C, Hamid YH, Joly E, Vaillant E, Benmezroua Y, Durand E, Bakaher N, Delannoy V, Vaxillaire M, Cook T, Dallinga-Thie GM, Jansen H, Charles MA, Clement K, Galan P, Hercberg S, Helbecque N, Charpentier G, Prentki M, Hansen T, Pedersen O, Urrutia R, Melloul D, Froguel P.  2005.  Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proc Natl Acad Sci U S A. 102(13):4807-12. Abstract