You are hereRecent Publications of Members of the Boston Ithaca Islet Club
Recent Publications of Members of the Boston Ithaca Islet Club
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2009
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2009. Adipose triglyceride lipase is implicated in fuel- and non-fuel-stimulated insulin secretion. J Biol Chem. 284(25):16848-59. Abstract
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2009. Evaluation of the antidiabetic potential of selected medicinal plant extracts from the Canadian boreal forest used to treat symptoms of diabetes: part II. Can J Physiol Pharmacol. 87(6):479-92. Abstract
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2009. Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass. Diabetologia. 52(6):1122-32. Abstract
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2009. Association of AMP-activated Protein Kinase Subunits With Glycogen Particles as Revealed In Situ by Immuno-electron Microscopy. J Histochem Cytochem. Abstract
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2009. Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial. Diabetologia. Abstract
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2009. Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations. Endocrinology. 150(8):3465-74. Abstract
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2009. Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PLoS One. 4(7):e6221. Abstract
2008
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2008. Glycerolipid metabolism and signaling in health and disease. Endocr Rev. 29(6):647-76. Abstract
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2008. The islet beta-cell: fuel responsive and vulnerable. Trends Endocrinol Metab. 19(8):285-91. Abstract
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2008. Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb J. 22(6):1905-13. Abstract
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2008. Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism. Diabetes. 57(8):1999-2011. Abstract
2007
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2007. Upregulation of cellular triacylglycerol - free fatty acid cycling by oleate is associated with long-term serum-free survival of human breast cancer cells. Biochem Cell Biol. 85(3):301-10. Abstract
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2007. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature. 445(7130):881-5. Abstract
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2007. A role for ATP-citrate lyase, malic enzyme, and pyruvate/citrate cycling in glucose-induced insulin secretion. J Biol Chem. 282(49):35657-65. Abstract
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2007. Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats. Appl Physiol Nutr Metab. 32(2):241-8. Abstract
2006
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2006. Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling. Diabetologia. 49(9):2120-30. Abstract
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2006. Anti-diabetic properties of the Canadian lowbush blueberry Vaccinium angustifolium Ait. Phytomedicine. 13(9-10):612-23. Abstract
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2006. Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance. Diabetes. 55(5):1421-9. Abstract
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2006. Islet beta cell failure in type 2 diabetes. J Clin Invest. 116(7):1802-12. Abstract
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2006. Fatty acid signaling in the beta-cell and insulin secretion. Diabetes. 55 Suppl 2:S16-23. Abstract
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2006. Selected plant species from the Cree pharmacopoeia of northern Quebec possess anti-diabetic potential. Can J Physiol Pharmacol. 84(8-9):847-58. Abstract
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2006. EIF4A2 is a positional candidate gene at the 3q27 locus linked to type 2 diabetes in French families. Diabetes. 55(4):1171-6. Abstract
2005
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2005. AMP-activated protein kinase and coordination of hepatic fatty acid metabolism of starved/carbohydrate-refed rats. Am J Physiol Endocrinol Metab. 289(5):E794-800. Abstract
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2005. Adenosine 5'-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes. Endocrinology. 146(5):2285-94. Abstract
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2005. Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function. Proc Natl Acad Sci U S A. 102(13):4807-12. Abstract