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Recent Publications of Members of the Boston Ithaca Islet Club


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2009
Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.  2009.  Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2. Mol Cell Biol. 29(11):3219-28. Abstract
Delghingaro-Augusto V, Nolan CJ, Gupta D, Jetton TL, Latour MG, Peshavaria M, Madiraju SR, Joly E, Peyot ML, Prentki M, Leahy J.  2009.  Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass. Diabetologia. 52(6):1122-32. Abstract
2008
Black AT, Gray JP, Shakarjian MP, Laskin DL, Heck DE, Laskin JD.  2008.  Increased oxidative stress and antioxidant expression in mouse keratinocytes following exposure to paraquat. Toxicol Appl Pharmacol. 231(3):384-92. Abstract
DeAngelis AM, Heinrich G, Dai T, Bowman TA, Patel PR, Lee SJ, Hong EG, Jung DY, Assmann A, Kulkarni RN, Kim JK, Najjar SM.  2008.  Carcinoembryonic antigen-related cell adhesion molecule 1: a link between insulin and lipid metabolism. Diabetes. 57(9):2296-303. Abstract
Black AT, Gray JP, Shakarjian MP, Mishin V, Laskin DL, Heck DE, Laskin JD.  2008.  UVB light upregulates prostaglandin synthases and prostaglandin receptors in mouse keratinocytes. Toxicol Appl Pharmacol. 232(1):14-24. Abstract
Boni-Schnetzler M, Thorne J, Parnaud G, Marselli L, Ehses JA, Kerr-Conte J, Pattou F, Halban PA, Weir GC, Donath MY.  2008.  Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation. J Clin Endocrinol Metab. 93(10):4065-74. Abstract
Kang G, Leech CA, Chepurny OG, Coetzee WA, Holz GG.  2008.  Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells. J Physiol. 586(5):1307-19. Abstract
Maedler K, Schulthess FT, Bielman C, Berney T, Bonny C, Prentki M, Donath MY, Roduit R.  2008.  Glucose and leptin induce apoptosis in human beta-cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. Faseb J. 22(6):1905-13. Abstract
2007
Pi J, Bai Y, Zhang Q, Wong V, Floering LM, Daniel K, Reece JM, Deeney JT, Andersen ME, Corkey BE, Collins S.  2007.  Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. 56(7):1783-91. Abstract
Pissios P, Ozcan U, Kokkotou E, Okada T, Liew CW, Liu S, Peters JN, Dahlgren G, Karamchandani J, Kudva YC, Kurpad AJ, Kennedy RT, Maratos-Flier E, Kulkarni RN.  2007.  Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes. 56(2):311-9. Abstract
Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, Wolfe MM.  2007.  Glucose-dependent insulinotropic polypeptide enhances adipocyte development and glucose uptake in part through Akt activation. Gastroenterology. 133(6):1796-805. Abstract
Marchetti P, Bugliani M, Lupi R, Marselli L, Masini M, Boggi U, Filipponi F, Weir GC, Eizirik DL, Cnop M.  2007.  The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients. Diabetologia. 50(12):2486-94. Abstract
Liang G, Cline GW, Macica CM.  2007.  IGF-1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination. Glia. 55(6):632-41. Abstract
Latour MG, Alquier T, Oseid E, Tremblay C, Jetton TL, Luo J, Lin DC, Poitout V.  2007.  GPR40 is necessary but not sufficient for fatty acid stimulation of insulin secretion in vivo. Diabetes. 56(4):1087-94. Abstract
Kibbey RG, Pongratz RL, Romanelli AJ, Wollheim CB, Cline GW, Shulman GI.  2007.  Mitochondrial GTP regulates glucose-stimulated insulin secretion. Cell Metab. 5(4):253-64. Abstract
2006
Perera HK, Caldwell ME, Hayes-Patterson D, Teng L, Peshavaria M, Jetton TL, Labosky PA.  2006.  Expression and shifting subcellular localization of the transcription factor, Foxd3, in embryonic and adult pancreas. Gene Expr Patterns. 6(8):971-7. Abstract
Wang L, Huang J, Saha P, Kulkarni RN, Hu M, Kim Y, Park K, Chan L, Rajan AS, Lee I, Moore DD.  2006.  Orphan receptor small heterodimer partner is an important mediator of glucose homeostasis. Mol Endocrinol. 20(11):2671-81. Abstract
List JF, He H, Habener JF.  2006.  Glucagon-like peptide-1 receptor and proglucagon expression in mouse skin. Regul Pept. 134(2-3):149-57. Abstract
Getty-Kaushik L, Song DH, Boylan MO, Corkey BE, Wolfe MM.  2006.  Glucose-dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification. Obesity (Silver Spring). 14(7):1124-31. Abstract
Heart E, Corkey RF, Wikstrom JD, Shirihai OS, Corkey BE.  2006.  Glucose-dependent increase in mitochondrial membrane potential, but not cytoplasmic calcium, correlates with insulin secretion in single islet cells. Am J Physiol Endocrinol Metab. 290(1):E143-E148. Abstract
He Z, Opland DM, Way KJ, Ueki K, Bodyak N, Kang PM, Izumo S, Kulkarni RN, Wang B, Liao R, Kahn CR, King GL.  2006.  Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. Arterioscler Thromb Vasc Biol. 26(4):787-93. Abstract
2005
Noguchi H, Bonner-Weir S, Wei FY, Matsushita M, Matsumoto S.  2005.  BETA2/NeuroD protein can be transduced into cells due to an arginine- and lysine-rich sequence. Diabetes. 54(10):2859-66. Abstract
Pelletier A, Joly E, Prentki M, Coderre L.  2005.  Adenosine 5'-monophosphate-activated protein kinase and p38 mitogen-activated protein kinase participate in the stimulation of glucose uptake by dinitrophenol in adult cardiomyocytes. Endocrinology. 146(5):2285-94. Abstract
Kang G, Chepurny OG, Rindler MJ, Collis L, Chepurny Z, Li WH, Harbeck M, Roe MW, Holz GG.  2005.  A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells. J Physiol. 566(Pt 1):173-88. Abstract
Hu Z, Dai Y, Prentki M, Chohnan S, Lane MD.  2005.  A role for hypothalamic malonyl-CoA in the control of food intake. J Biol Chem. 280(48):39681-3. Abstract